Pharmaceutical Sciences Jobs Latest at Syngene
Syngene International Ltd., a global leader in discovery, development, and manufacturing services, is hiring an In Vitro ADME Scientist for its Discovery Biology department in Hyderabad. This role offers the opportunity to work on advanced in-vitro ADME assays, collaborate with cross-functional teams, and contribute to impactful research for top pharmaceutical and biotechnology clients worldwide.
- Job Title: In Vitro ADME Scientist
- Job Location: Hyderabad
- Department: Discovery Biology
About Syngene
Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development, and manufacturing organization that provides integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical industries worldwide. Its clientele includes world-leading companies such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA, and Herbalife. Syngene’s innovative culture is driven by a team of 4240 scientists working passionately with clients to solve scientific problems, increase R&D productivity, accelerate time to market, and reduce the cost of innovation.
Educational Qualification
MPharm in Pharmaceutical Sciences
Experience
1-4 years of industrial experience in DMPK/ADME research with an M Pharm in pharmaceutical sciences
Job Purpose
The Invitro ADME Scientist will support the ADME team by conducting high-quality in vitro assays, including metabolic stability and CYP inhibition studies using human liver microsomes. The role involves managing multiple projects within strict timelines, maintaining accurate lab records, and ensuring a safe and organized laboratory environment. This is a predominantly laboratory-based position requiring strong technical and time-management skills.
Key Responsibilities
- Plan and execute in vitro single-point inhibition, reversible CYPIC50 inhibition, and TDI-IC50 shift assays.
- Coordinate with the BA-DMPK group to design in vitro CYP inhibition studies.
- Prepare SOPs and EOPs and ensure compliance in reporting study results.
- Adhere to EHS requirements for individual and lab/plant safety.
Technical/Functional Skills
- Comprehensive understanding of in vitro ADME assays and troubleshooting expertise.
- Knowledge of enzyme kinetics, as well as proficiency in software such as Microsoft Excel and GraphPad Prism.
- Experience with automation is desirable.
Behavioral Skills
- Team player with a commitment to the timely delivery of study reports.
- Adaptability to changes in the laboratory environment.
- Strong communication skills for presentations in scientific meetings and peer-reviewed journals.
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