Pharma QC Jobs | HPLC / GC | MSN Labs Hiring
Job Title
Senior QC Executive (HPLC / GC)
Company: MSN Laboratories
Location: Hyderabad, Telangana (On-site)
CTC / Base Salary: ₹3.10 LPA – ₹7.00 LPA (depending on experience, skills and fit)
Experience: 3 – 7 years in pharmaceutical analytical QC (preferably HPLC/GC focus)
Employment Type: Full-time (Permanent) — Probation as per company policy (typically 3–6 months)
Job Summary
We are seeking a hands-on Senior QC Executive with strong expertise in analytical techniques (HPLC and GC) to join the Quality Control team at our Hyderabad facility. The role involves execution and review of analytical testing, method validation/transfer support, troubleshooting chromatographic issues, ensuring GMP-compliant documentation, and driving timely sample throughput while maintaining the highest quality standards.
Key Responsibilities
Analytical Testing & Method Execution
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Perform routine and non-routine analysis of raw materials, in-process samples, finished products, and stability samples using HPLC and GC as per approved methods and SOPs.
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Execute system suitability, blank and standard runs, calibration, and instrument verification.
Method Development, Validation & Transfer Support
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Support method development, optimization, validation, and robustness studies for HPLC/GC methods in collaboration with R&D/Analytical Development teams.
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Participate in method transfer activities and ensure successful cross-site method implementation.
Data Review & Reporting
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Review chromatograms, raw data, and analytical reports for accuracy, compliance and trend analysis; raise queries and corrective actions where required.
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Prepare and review analytical reports, validation protocols, and summaries as per documentation standards.
Troubleshooting & Instrument Maintenance
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Troubleshoot chromatographic issues (peak shape, retention, baseline noise, ghost peaks, carryover) and implement corrective measures.
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Routine preventive maintenance, instrument calibration, and coordination with service engineers for complex repairs; maintain instrument logbooks.
GMP & Documentation
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Ensure strict adherence to GMP, internal SOPs, data integrity requirements (ALCOA+), and GLP principles while performing and documenting analytical work.
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Manage deviations, out-of-specification (OOS) events, investigations, and change controls in coordination with QA.
Stability & Regulatory Support
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Execute stability sample testing and contribute to stability protocols and trend evaluations.
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Support regulatory inspections by providing required documentation, analytical justifications and timely responses.
Training & Mentoring
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Train and mentor junior analysts and technicians in analytical techniques, instrument handling, data review practices and GMP documentation.
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Provide technical guidance for shift handovers and maintain high team productivity.
Continuous Improvement
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Drive initiatives to improve lab throughput, reduce rework, increase method robustness and optimize consumable usage.
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Participate in 5S/Kaizen projects and implement laboratory best practices.
Required Qualifications & Skills
• Education: M.Sc. / M.Pharm / B.Pharm (Analytical Chemistry / Pharmaceutical Analysis) or B.Sc. (Chemistry) with strong analytical background. Candidates with diploma + relevant experience may be considered for some profiles.
• Experience: 3–7 years in pharmaceutical QC laboratory with hands-on experience in HPLC and GC operations, method validation and data review.
• Technical skills: Proficiency in chromatographic method execution, system suitability criteria, calibration and basic method troubleshooting.
• Instrumentation: Experience with HPLC (binary/pump systems, detectors like UV, PDA) and GC (FID/TCD) instruments and chromatography data systems (e.g., Empower, ChemStation, OpenLab etc.).
• Regulatory knowledge: Good understanding of GMP, GLP, data integrity (ALCOA+), stability testing and regulatory expectations for analytical laboratories.
• Computer skills: Comfortable with MS Office (Excel/Word) and LIMS/ERP exposure preferred.
• Personal skills: Strong analytical thinking, attention to detail, good documentation practices, effective communication and ability to work in teams and shifts.
Preferred / Desirable
• Proven experience in method development/validation and transfer for pharmaceutical matrices.
• Experience with hyphenated techniques (LC-MS) is a plus.
• Prior exposure to stability studies, forced degradation studies, dissolution and assay by HPLC.
• Certification or formal training in chromatography / analytical techniques is advantageous.
• Experience with instrument qualification (IQ/OQ/PQ) and calibration activities.
Key Performance Indicators (KPIs)
• Timely completion of sample analysis (% adherence to TAT)
• Number of OOS/OOT events and closure time
• Accuracy and compliance of analytical documentation (documentation error rate)
• Instrument uptime and preventive maintenance adherence
• Successful completion of method validations and transfers
• Training completion and performance of supervised junior staff
Reporting & Work Relationships
• Reports to: QC Section Lead / QC Manager
• Interacts with: QA, Production, Analytical Development / R&D, Stability, Stores and Engineering teams
Shift & Working Hours
• Role may require rotational shifts depending on lab operations; willingness to work nights/rotational shifts and overtime during critical schedules is required.
Compensation & Benefits (Indicative)
• Base CTC: ₹3.10 LPA – ₹7.00 LPA (based on experience, technical depth and negotiation)
• Performance linked incentives / bonuses as per company policy
• Statutory benefits: Provident Fund, ESI (if eligible), gratuity (as applicable)
• Health insurance, paid leaves, and other benefits per company norms
• Opportunity for training and career progression
Interview Process (Indicative)
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HR Screening (Round 1) – Telephonic/virtual screening for role fit, notice period and compensation expectations.
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Technical Interview (Round 2) – QC Manager / Senior Analyst: practical questions on HPLC/GC, method validation, data review, OOS investigations (virtual or on-site).
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Hands-on or Practical Assessment (Round 3) – Demonstration or discussion of chromatogram review, method troubleshooting or case study (on-site).
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Final / Management Round (Round 4) – Site Head / Department Head: offer discussion and final fitment.
How to Apply
Share an updated CV highlighting analytical experience (HPLC/GC), key projects (method validations, transfers), instruments handled, and current vs expected CTC.
